药物不良反应是指药品在正常用量下所出现的与治疗目的无关的反应和对人体的有害反应及药源性疾病。据有关资料报道,1996年上海曾发生一起轰动全国的药物不良反应事件,一退休职工因服用上海某药厂生产的“卡马西平”后,高热40℃,视力模糊、腹部绞痛、昏迷、全身皮肤粘膜糜烂,几天几夜呕血不止,其状惨不忍睹,医院开出“病危通知单”,诊断为“因卡马西平引起的多形红斑型药疹”,后经医院全力抢救,患者才脱离危险。该药的说明书中仅注明了“最常见的有眩晕、思睡、不安、恶心、呕吐等不良反应”,生产厂家擅自删去了上海市卫生局指定应注明的“皮疹、荨麻疹、白细 Adverse drug reactions refers to the drugs in the normal dosage of the treatment has nothing to do with the reaction and the body’s harmful reactions and drug-induced diseases. According to relevant information, in 1996 there was a sensational adverse drug reaction in Shanghai. A retired worker who took “carbamazepine” produced by a Shanghai pharmaceutical factory after suffering from a fever of 40 ° C, blurred vision, abdominal cramps, coma, Whole body skin and mucous membrane erosion, a few days and nights, hematemesis, the shape appalling, the hospital out of “critical notice”, diagnosed as “caused by carbamazepine erythema multiforme type of drug rash,” after the hospital full rescue, the patient was detached Danger. The drug’s instructions only indicate “the most common are dizziness, sleep, restlessness, nausea, vomiting and other adverse reactions,” the manufacturer without authorization designated by the Shanghai Municipal Health Bureau should be specified "rash, urticaria, White