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Colombo等指出,肝细胞癌(HCC),尤其是在血清抗-HBc阳性的肝硬变患者,其发生与丙型肝炎病毒(HCV)相关。目前认为,HCV是输血后非甲非乙型肝炎(PTH-NANB)的主要病原。本文作者报道了1例意大利PTH-NANB患者,从急性肝炎发展成慢性肝炎,然后为肝硬变,最后发展成肝细胞癌的过程。患者男性,58岁,1975年因心脏手术输入大量血浆。术前无任何肝病症状,肝脏检测正常,但抗-HBc和抗-HBs阳性。手术后10周,患者感到乏力、不适、厌食,并
Colombo et al. Show that hepatocellular carcinoma (HCC), especially in patients with serum anti-HBc-positive cirrhosis, is associated with hepatitis C virus (HCV). Currently, HCV is the major cause of post-transfusion non-A, non-B hepatitis (PTH-NANB). The authors of this report report a patient with PTH-NANB in Italy that progresses from acute hepatitis to chronic hepatitis, then to cirrhosis and eventually to hepatocellular carcinoma. Male patient, age 58, received large volumes of cardiac surgery in 1975. No symptoms of liver disease before surgery, the liver was normal, but anti-HBc and anti-HBs positive. Ten weeks after surgery, the patient feels tired, discomfort, anorexia, and