60例2型糖尿病患者随机分为两组:一组给予甘精胰岛素和门冬胰岛素治疗,一组给予中效和短效人胰岛素治疗,比较两组降糖效果、达标时间、胰岛素用量和低血糖事件发生率。结果:治疗后两组FPG、2HPG、胰岛素用量无显著性差异(P>0.05);达标时间:甘精组短于NPH组(P<0.01),低血糖事件发生率:甘精组低于NPH组(P<0.05)。结论:甘精胰岛素联合门冬胰岛素能有效模拟人的生理胰岛素分泌,尽早使血糖平稳达标,且低血糖发生率较低。 Sixty patients with type 2 diabetes were randomly divided into two groups: one was given insulin glargine and insulin aspart, one was treated with short-acting human insulin and short-acting insulin. The hypoglycemic effect, time to target, insulin dosage and low The incidence of blood sugar events. Results: After treatment, there was no significant difference in the dosage of FPG, 2HPG and insulin between the two groups (P> 0.05); the time of reaching the standard was shorter in Gan Gan group than in NPH group (P <0.01); The incidence of hypoglycemia was lower in Gan Gan group than in NPH group Group (P <0.05). Conclusion: Insulin glargine combined with insulin asparts can effectively simulate the physiological insulin secretion, as soon as possible so that blood glucose reached the standard, and low incidence of hypoglycemia.