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目前根据脑脊液常规方法检测中枢神经系统白血病(CNSL)还不够敏感。我们于1986年1月至1987年4月观察了急性白血病患者脑脊液β_2微球蛋白(β_2-m)的变化,探讨其对CNSL的诊断意义。β_2-m是一种细胞膜蛋白,是HLA的轻链,它可作为淋巴系统肿瘤增殖的标志。本文合并CNSL11例,其CST的β_2-m浓度明显高于对照组和无CNSL组,比较同时测
At present, detecting cerebrospinal fluid (CSF) is not sensitive enough to detect central nervous system leukemia (CNSL). We observed the change of cerebrospinal fluid β_2 microglobulin (β_2-m) in patients with acute leukemia from January 1986 to April 1987, and explored its diagnostic significance for CNSL. β_2-m is a cell membrane protein that is a light chain of HLA that can be used as a marker of tumor proliferation in the lymphatic system. In this paper, CNSL11 cases, the CST β_2-m concentration was significantly higher than the control group and no CNSL group, compared with simultaneous testing