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目的:分析广州市妇女人乳头瘤病毒(human papilloma virus,HPV)的感染率及相关因素,为女性HPV的防治提供科学依据。方法:采用以医院为基础的现况研究方法,对接受宫颈HPV检测的592例女性进行问卷调查。结果:592例共检出HPV阳性474例,HPV总感染率为80.1%。单因素非条件Logistic回归分析中,HPV感染的保护因素为高年龄、初次性生活年龄大、收入高及参加筛查。孕次多和性伴侣数多是HPV感染的危险因素。多因素非条件Logistic回归显示,HPV感染的保护因素为初次性生活年龄大、收入高、参加筛查。结论:初次性生活年龄较大、收入高和参加筛查的妇女感染HPV的概率低,提示应该提高妇女的经济收入,提倡初次性生活年龄最好在20岁以后,同时应重视HPV的筛查,尽可能做到早期发现,及时进行规范性治疗。
Objective: To analyze the infection rate and related factors of human papilloma virus (HPV) in Guangzhou women and provide a scientific basis for the prevention and treatment of HPV in women. METHODS: A hospital-based study of the current status of 592 women who underwent cervical HPV testing was conducted. Results: A total of 474 HPV positive cases were detected in 592 cases, the total HPV infection rate was 80.1%. In the univariate non-conditional Logistic regression analysis, the protective factors of HPV infection were high age, first-time sexual life, high income and participation in screening. Multiple pregnancies and more sexual partners are risk factors for HPV infection. Multivariate non-conditional logistic regression showed that the protective factors of HPV infection were the age of first-time sexual life, high income and participation in screening. CONCLUSIONS: The low probability of HPV infection among women with first-time sex, high income, and screening may indicate that the economic income of women should be increased, and the first-time sex life should be advocated after 20 years of age, with emphasis on HPV screening , As far as possible to achieve early detection, timely normative treatment.