急性脑梗死是临床多发病和常见病，其后果严重，给人类健康带来严重的危害，且不同患者的预后差异很大，因而对脑梗死患者的预后判断显得至关重要。近年来，随着研究的深入，血浆生物学标志物（如同型半胱氨酸、尿酸、纤维蛋白原等）与脑梗死预后的关系成为研究的热点。而不同类别的血浆生物标志物在脑梗死发生、发展过程中所起的作用也不尽相同。“,”The acute cerebral infarction is a highly prevalent disease.With its bad consequences,the acute cerebral infraction threatens human health.It is crucial for the judgment of the prognosis of ACI patients due to the various prognosis conditions with different patients .Currently the relationship between plasma bio-markers, such as homocysteine, uric acid, fibrinogen and the prognosis of cerebral infarction has already become a hotspot in the field,and it′s found that different plasma biomarkers play different roles for the initi-ation and progression of cerebral infarction.