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目的探讨老年糖尿病能量代谢的特点。方法对21例老年男性糖尿病人与22例健康老年人采用间接测热法,进行静息能量消耗(REE)的测定。结果糖尿病组与对照组比较,年龄、体重、体重指数、脂肪含量均无显著性差异(P>0.05)。糖尿病人组REE值(1392.21±259.20)较对照组(1639.27±344.76)明显减低(P<0.05)。结论老年糖尿病的代谢紊乱之一表现为静息能量消耗降低,其原因可能和糖尿病人的植物神经功能失衡导致瘦素等激素水平改变有关。
Objective To investigate the characteristics of energy metabolism in senile diabetes. Methods Twenty-one elderly men with diabetes and 22 healthy controls were enrolled in this study. The resting energy expenditure (REE) was measured by indirect calorimetry. Results There were no significant differences in age, body weight, body mass index and fat content between diabetic group and control group (P> 0.05). The level of REE in diabetic group (1392.21 ± 259.20) was significantly lower than that in control group (1639.27 ± 344.76) (P <0.05). Conclusions One of the metabolic disorders of senile diabetes is the decrease of resting energy expenditure. The reason may be related to the imbalance of autonomic function of leptin and other hormones in diabetic patients.