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目的 探讨重肺型炎并发抗利尿激素分泌异常对血循环的影响。方法 对48 例重型肺炎小儿血、尿电解质、渗透压、抗利尿激素(ADH) 及心功能进行了对比研究。结果 13 例在肺炎极期出现尿少、体重增加、急性肺水肿表现,同时血钠、血浆渗透压下降,尿钠、尿渗透压升高、血浆ADH 增高,而心功能测定正常,为并发抗利尿激素异常分泌综合征(SIADH)。经过限水、利尿、补钠治疗,临床症状改善,血、尿指标恢复正常。结论 重型肺炎并发SIADH可引起非心源性循环充血症状,易与心力衰竭混淆,临床医师应注意识别。
Objective To investigate the effect of abnormal secretion of antidiuretic hormone on blood circulation in patients with severe pulmonary pneumonia. Methods 48 cases of severe pneumonia in children with blood, urine electrolytes, osmotic pressure, anti-diuretic hormone (ADH) and cardiac function were compared. Results Thirteen cases showed oliguria, weight gain and acute pulmonary edema in the extreme period of pneumonia. At the same time, serum sodium and plasma osmotic pressure decreased, urine sodium and urine osmotic pressure increased, plasma ADH increased, and cardiac function was normal Diuretic hormone abnormal secretion syndrome (SIADH). After water, diuretic, sodium supplementation, clinical symptoms improved, blood, urine indicators returned to normal. Conclusions Severe pneumonia complicated with SIADH can cause non-cardiac circulatory congestion symptoms and is easily confused with heart failure. Clinicians should pay attention to the identification.