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Objective:The aim of the study was to explore the efficacy of three-dimensional conformal radiotherapy(3DCRT) combined with TP concurrent chemotherapy in treatment of recurrent cervical cancers.Methods:From May 2005 to May 2009,36 patients with recurrent cervical cancer were treated by 3D-CRT of 60-66 Gy and TP(docetaxel 70 mg/m2,d1;cisplatin 20 mg/m2,d1-d3;21 days per cycle,totally 2 cycles) concurrent chemotherapy.Results:All of the patients had finished the 3D-CRT,the total response rate,complete response rate and partial response rate were 80.0%(28/35),45.7%(16/35),and 34.3%(12/35),respectively.The pain-alleviation rate was 91.4%(32/35).The hemorrhage control rate was 94.3%(33/35).The median overall survival was 21.2 months.The 1-,2-and 3-year survival rates were 54.3%,37.1% and 22.8%,respectively.The life qualities of the patients were improved,without any treatment related death.Conclusion:Radiotherapy is effective and well-tolerated for recurrent cervical cancers,and it can promote regional control of the disease and prolong survival time.
Objective: The aim of the study was to explore the efficacy of three-dimensional conformal radiotherapy (3DCRT) combined with TP concurrent chemotherapy in treatment of recurrent cervical cancers. Methods: From May 2005 to May 2009, 36 patients with recurrent cervical cancer were treated by 3D-CRT of 60-66 Gy and TP (docetaxel 70 mg / m2, d1; cisplatin 20 mg / m2, d1-d3; 21 days per cycle, totally 2 cycles) concurrent chemotherapy. Results: All of the patients had finished The 3D-CRT, the total response rate, complete response rate and partial response rate were 80.0% (28/35), 45.7% (16/35), and 34.3% (12/35), respectively.The pain-alleviation rate The median overall survival was 21.2 months. The 1-, 2-and 3-year survival rates were 54.3%, 37.1% and 22.8 %, respectively. The life qualities of the patients were improved, without any treatment related death. Conlusion: Radiotherapy is effective and well-tolerated for recurrent cervical cancers, and it can prom ote regional control of the disease and prolong survival time.