论文部分内容阅读
探讨免疫表型在急性早幼粒细胞白血病中的表达。方法：通过免疫荧光显微镜，利用单克隆抗体分析１４例Ｍ_３患者的初诊免疫表型。结果：各髓系抗原的表达率依次为ＣＤ_３３＞ＣＤ_１３＞ＣＤ_１５。所有患者ＣＤ_９阳性，但是不表达ＣＤ_３４和ＨＬＡ－ＤＲ，并且不表达ＣＤ_２。结论：结合ＣＤ_９抗原及其它免疫学标记的联合应用可为临床提供诊断依据。同时对于ＣＤ_２~＋是否可作为Ｍ_３表型特征之—有待于积累更多病例方可评论。
To investigate the expression of immunophenotype in acute promyelocytic leukemia. Methods: The immunophenotypes of 14 M 3 patients were analyzed by immunofluorescence microscopy and monoclonal antibody. Results: The expression rates of myeloid antigens were CD_33> CD_13> CD_15. All patients were positive for CD_9, but not for CD_34 and HLA-DR, and did not express CD_2. Conclusion: The combination of CD_9 antigen and other immunological markers may provide a basis for clinical diagnosis. At the same time whether CD_2 ~ + can be used as M_3 phenotype characteristics - to be accumulated in more cases before commenting.