肝硬化患者血浆尾加压素水平与肾动脉阻力的变化

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目的探讨肝硬化时血浆尾加压素Ⅱ(uⅡ)水平与肾动脉血流阻力指数的变化。方法对26例健康对照者和46例肝硬化患者(按照Child-Pugh分级将病例分为A,B,C三组),采用酶联免疫吸附法(ELISA)测定血浆uⅡ含量;同时行彩色多普勒超声检查,测定肾动脉血流阻力指数(RI);并测定血肌酐(scr),应用MDRD(Modification of Diet in Renal Disease)公式估计肌酐清除率(CCr)。结果肝硬化各组血浆uⅡ与肾动脉RI均显著高于对照组;而A级患者的CCr水平与对照组相比,差
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