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二甲双胍作为一种双胍类降血糖药物,因在2型糖尿病的治疗上效果优越而被知晓,临床上长时间在糖尿病患者中应用,其安全性已能得到保证,常见副作用是胃肠道的不适症状,最严重的副作用是乳酸酸中毒。目前已经有诸多研究报告称二甲双胍具有抗肿瘤作用,且包含不同肿瘤应用二甲双胍的疗效,并提供了其抗肿瘤作用的证据。不过其抗肿瘤作用还有待临床更多学者进一步更深入的研究,本文亦对二甲双胍治疗多种类型肿瘤的效果进行研究与探索,以为临床提供一些有价值的依据。
As a biguanide hypoglycemic drug, metformin is known for its superior efficacy in the treatment of type 2 diabetes and its safety has been assured for a long time to be used clinically in diabetic patients. The common side effect is gastrointestinal discomfort Symptoms, the most serious side effect is lactic acidosis. There are many studies reported that metformin has anti-tumor effect, and contains different tumors with metformin curative effect, and provides evidence of its anti-tumor effect. However, its antitumor effect remains to be further studied by more scholars in clinical practice. This article also studies and explores the efficacy of metformin in the treatment of various types of tumors in order to provide some valuable evidences for clinical practice.