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目的 观察催产素与间苯三酚联合应用在足月孕引产过程中的疗效。方法 收集2009～2010年成都市妇女儿童中心医院计划分娩行催产素引产的正常足月妊娠孕妇100例,随机分为观察组和对照组,每组各50例。观察组采用催产素与间苯三酚联合应用,对照组单用催产素,观察两组孕妇产程的变化及胎儿情况。结果 第一产程时间观察组(412±20)min明显短于对照组(686±38)min,差异有统计学意义(P<0.05)。经阴道分娩率、新生儿Apgar评分观察组均优于对照组,但差异无统计学意义(P>0.05);新生儿窒息与产后出血发生率观察组均低于对照组,但差异无统计学意义(P>0.05)。结论 催产素与间苯三酚联合应用可以明显缩短第一产程,从而提高引产成功率。
Objective To observe the curative effect of oxytocin combined with phloroglucinol in induction of labor during term pregnancy. Methods A total of 100 full-term pregnant women who were scheduled for delivery of oxytocin and induced labor were collected from Chengdu Women and Children’s Central Hospital between 2009 and 2010. They were randomly divided into observation group and control group with 50 cases in each group. Oxytocin and phloroglucinol were used in the observation group. Oxytocin was used alone in the control group to observe the change of labor process and the fetus in the two groups. Results The time of first stage of labor observation group (412 ± 20) min was significantly shorter than that of control group (686 ± 38) min, the difference was statistically significant (P <0.05). Vaginal delivery rate, neonatal Apgar score were better than the control group observation group, but the difference was not statistically significant (P> 0.05); neonatal asphyxia and postpartum hemorrhage incidence were observed in the observation group were lower than the control group, but the difference was not statistically significant Significance (P> 0.05). Conclusion oxytocin combined with phloroglucinol can significantly shorten the first stage of labor, thereby increasing the success rate of induction of labor.