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目的分析伴脑干萎缩的基底节生殖细胞瘤临床特点及影像学改变,以提高对此病的认识。方法结合文献分析7例基底节生殖细胞瘤患者的临床和影像学特征。结果7例患者均为年轻男性,主要表现为缓慢进展的轻偏瘫;影像学显示肿瘤主要位于基底节,MRIT1加权像上呈低或等低混杂信号,T2加权像上呈高或等高混杂信号,伴有同侧大脑半球或脑干萎缩。结论基底节生殖细胞瘤临床及影像学缺乏特异性;年轻患者出现缓慢进行性偏瘫,伴有病变同侧大脑偏侧萎缩或/和大脑脚萎缩的基底节病变应高度怀疑基底节生殖细胞瘤。
Objective To analyze the clinical features and imaging changes of basal cell germ cell tumors with atrophy of brain stem in order to improve the understanding of this disease. Methods Combined with literature analysis of 7 patients with basal cell germ cell tumors of the clinical and imaging features. Results All the 7 patients were young men. The main manifestations were mild hemiparesis with slow progress. Imaging showed that the tumors were mainly located in the basal ganglia. MRIT1 weighted images showed low or low mixed signals, and T2 weighted images showed high or high mixed signals , Accompanied by ipsilateral cerebral hemisphere or brainstem atrophy. Conclusions Basal ganglia germ cell tumors are not clinically and radiologically specific; basil ganglia germ cell tumors should be highly suspected in young patients with progressive progressive hemiplegia, with atrophy of the ipsilateral cerebral atrophy or / and atrophy of the cerebral peduncle.