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目的:脑胶质瘤是人体颅内最为多见的恶性肿瘤。方法:现有的手术+放疗+化疗的综合治疗措施仍难以根治。结果:树突状细胞(Dendritic cell,DC)作为体内功能最强大的专职抗原递呈细胞(APC),能够诱导特异性的细胞毒性T淋巴细胞(CTL)生成。结论:本文就DC疫苗在脑胶质瘤治疗研究中的现状及进展进行综述。
Objective: Glioma is the most common intracranial malignant tumor. Methods: The current comprehensive treatment of surgery + radiotherapy + chemotherapy is still difficult to cure. Results: Dendritic cell (DC), as the most potent professional antigen-presenting cell (APC) in the body, can induce the formation of specific cytotoxic T lymphocytes (CTLs). Conclusion: This review summarizes the current status and progress of DC vaccines in the treatment of glioma.