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目的为控制ＨＢＶ慢性携带者进入航校提供对策，对应招飞行学员中ＨＢｓＡｇ阴性者的ＨＢＶ感染情况及对ＨＢＶ的免疫状态作一探讨。方法用ＥＬＩＳＡ法检测ＨＢｓＡｇ、抗－ＨＢｓ、抗－ＨＢｃ、ＨＢｅＡｇ、抗－ＨＢｅ，用聚合酶链反应（ＰＣＲ）检测ＨＢＶ－ＤＮＡ。结果ＨＢｓＡｇ阴性应招飞行学员中抗－ＨＢｓ阳性２０６／９６２例（２７．６％），抗ＨＢｃ阳性２２９／９６２例（２２．８％），ＨＢｅＡｇ阳性０／４５０例，抗ＨＢｅ阳性３／４５０例（０．６７％），ＨＢＶ－ＤＮＡ阳性１５／２２８例（６．６％）。ＨＢＶ－ＤＮＡ阳性主要集中在单一抗ＨＢｃ阳性者中１４／７５例（１８．７％）。获得ＨＢＶ免疫者为３４．０％。结论在应招飞行学员中对单一抗ＨＢｃ阳性者应做ＨＢＶ－ＤＮＡ检测，未获ＨＢＶ免疫者应接种乙肝疫苗
Objective To provide a countermeasure for controlling the chronic carriers of HBV to enter the school of navigation, corresponding to the HBV infection among HBsAg-negative students who entertained the pilots and to investigate the immune status of HBV. Methods HBsAg, anti-HBs, anti-HBc, HBeAg and anti-HBe were detected by ELISA. HBV-DNA was detected by polymerase chain reaction (PCR) Results HBsAg negative students should fly flight 206/962 (27.6%) positive anti-HBc positive 229/962 (22.8%), HBeAg positive 0/450 cases anti-HBe positive 3/450 cases (0.67%), HBV DNA positive 15/228 cases (6.6%). HBV-DNA positive was mainly concentrated in 14/75 cases (18.7%) of single anti-HBc positive. Obtained HBV immunization was 34.0%. Conclusions The HBV-DNA test should be done on the single anti-HBc positive students who should fly in the flight, and the hepatitis B vaccine