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作者报告了20年治疗观察的5例鼻内鳞状细胞癌,最初都被认为是鼻部良性皮肤病,后来经 X 线检查及深部皮肤活检才明确诊断。5例患者,女性2例,男性3例,年龄除1例为22岁外,其余4例为57～73岁。发病至就诊时间为2～18个月。最初均表现为鼻部皮肤肿胀、疼痛触痛、发红。1例损害上有多个窦道并有脓液排出,2例发生鼻塞及间断性鼻出血。有4例最初诊断为鼻部皮肤感染,1例多次诊断为继发于外伤、酒渣鼻或红斑狼疮。5例都用过红霉素或青霉素、四环素等多种抗生素治疗,均无效。1例最初曾作表浅的皮肤活检,显示
The authors reported 5 cases of intranasal squamous cell carcinoma treated for 20 years. They were initially considered as benign nasal skin diseases and were diagnosed by X-ray examination and deep skin biopsy. There were 5 patients, 2 women and 3 men. The age was 1 year except 22 years old, and the remaining 4 cases were 57-73 years old. Onset to treatment time is 2 to 18 months. The initial manifestations were nasal swelling, painful tenderness, and redness. In one case, there were multiple sinuses with pus discharge, and two cases of nasal congestion and intermittent epistaxis. Four cases were initially diagnosed with nasal skin infections, and one case was diagnosed secondary to trauma, rosacea, or lupus erythematosus. All 5 cases were treated with erythromycin or penicillin, tetracycline and other antibiotics and were ineffective. One case had a superficial skin biopsy and showed