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作者根据当地耐氯奎恶性疟疾发生率高达50-100％,对此类病例选用磺胺甲氧吡嗪1克与甲氧苄氨嘧啶0.5克一次顿服(以下简称SF-T组),或选用周效磺胺1克与乙胺嘧啶0.05克一次顿服(以下简称S-P组),共治疗恶性疟88人。观察退热时间,疟原虫消失情况及有无复发,并观察红细胞中G-6PD有缺陷的病人服药后有何影响。疟原虫抗体的有无,是否影响疗效。
According to the local incidence of chloroquine resistant malignant malaria incidence of up to 50-100%, for such cases the choice of sulfamethoxazole 1 g and trimethoprim 0.5 g once served (hereinafter referred to as SF-T group), or use Weekly sulfonamide 1 g and pyrimethamine 0.05 g once Dayton clothing (hereinafter referred to as SP group), a total of 88 cases of falciparum malaria. Observe the time of fever, the disappearance of parasite and the presence or absence of recurrence, and observe the impact of G-6PD-deficient patients on the erythrocytes after taking the drug. Plasmodium antibodies, whether or not, affect the efficacy.