论文部分内容阅读
对癌症患者来说,转移是治疗失败的主要原因。迫切需要建立新的临床方法:(a)预测患者肿瘤的侵袭。(b)局限并破坏体内转移灶的生长。所以,对肿瘤科学工作者的主要挑战是确定在转移性瘤细胞中增长且在功能上与肿瘤恶性有关的生化因子(特殊的基因产物)。这些因子含量的测定可提供对患者肿瘤侵袭的预测指标。针对同一种转移因子的抗体,可用于免疫放射闪烁法(扫描)来定位临床无症状的转移。能结合和/或封闭这些转移因子的药物,在治疗转移中可能是很有用的。转移是复杂的连续步骤的最终结果。人
For cancer patients, metastasis is the main reason for treatment failure. There is an urgent need to establish new clinical methods: (a) Predict the invasion of a patient’s tumor. (b) Limit and destroy the growth of metastases in the body. Therefore, the main challenge for oncologists is to identify biochemical factors (special gene products) that increase in metastatic tumor cells and are functionally related to tumor malignancy. Determination of the levels of these factors can provide predictors of tumor invasion in patients. Antibodies against the same transfer factor can be used in immunoradiography (scanning) to locate clinically asymptomatic metastases. Drugs that bind to and/or block these transfer factors may be useful in the treatment of metastases. Transfer is the final result of a complex series of steps. people