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目的探讨酪酸梭菌活菌颗粒加醒脾养儿颗粒中西医联合治疗婴幼儿慢性腹泻病的疗效。方法慢性腹泻患儿221例,随机分为两组,治疗组112例,对照组109例。治疗组给酪酸梭菌活菌颗粒调节肠道菌群,增强肠道抵抗能力,同时口服醒脾养儿颗粒;对照组给枯草杆菌肠球菌颗粒加蒙脱石散口服。合并脱水者给予补液治疗,纠正脱水,在治疗中不改变患儿饮食,观察两组大便次数和性状的变化。结果治疗3d总有效率治疗组与对照组分别为91.5%和65.1%,差异有统计学意义(P<0.01)。结论酪酸梭菌活菌颗粒加醒脾养儿颗粒中西医联合治疗婴幼儿慢性腹泻疗效好,值得临床应用。
Objective To investigate the curative effect of Clostridium butyricum granules combined with xing spleen Yanger granule on treating chronic diarrhea in infants with integrated traditional Chinese and western medicine. Methods 221 children with chronic diarrhea were randomly divided into two groups: 112 cases in the treatment group and 109 cases in the control group. The treatment group to Clostridium butyricum viable particles regulate intestinal flora, enhance intestinal resistance, while oral spleen Yangner particles; control group to Bacillus subtilis entericciton plus montmorillonite oral. Patients with dehydration were given rehydration therapy to correct dehydration, in the treatment does not change the children’s diet, observe the changes in stool frequency and traits. Results The total effective rate of treatment for 3 days was 91.5% in the treatment group and 65.1% in the control group, the difference was statistically significant (P <0.01). Conclusion Clostridium butyricum viable particles plus Xingnao Yang particles in the treatment of chronic diarrhea in infants and young children is effective and worthy of clinical application.