患儿,女,20个月,足月顺产,第1胎,产后情况良好,发育较同龄儿迟缓,搀扶才能走路,智能低下,语言能力差,父母体健。非近亲结婚, 体检:体重9.2kg,身长26.5cm,上部45cm,头围45cm,皮肤白皙,头发黄,扁头形,前囱未关,仍有指头大小,颈部淋巴结未见明显肿大,鼻根部较扁平,眼距较宽,眼裂平,两眼无神,角膜映照点位置:左眼在瞳孔的中央,右眼在角膜 Children, women, 20 months, term full-term pregnancy, the first child, postnatal well, development is slower than the same age, help to walk, mental retardation, poor language skills, parents physical health. Non-relatives married, physical examination: weight 9.2kg, height 26.5cm, upper 45cm, head circumference 45cm, fair-skinned, yellow hair, flat head shape, the front chimney is not closed, there is still finger size, neck lymph node was not significantly enlarged, The nasal root is flat, wider eyes, eyes split level, two atheism, corneal mapping point position: the left eye in the pupil of the center of the right eye in the cornea