利培酮联合阿立哌唑治疗精神分裂症对患者疗效及生活质量的影响

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目的 研究观察利培酮联合阿立哌唑治疗精神分裂症对患者疗效及生活质量的影响.方法 选择我院2019年1月至2020年2月收治的88例精神分裂症患者作为研讨对象,根据治疗方法的不同,把患者分为两组,其中一组为对照组,实施利培酮治疗,一组为观察组,实施利培酮联合阿立哌唑治疗,均44例;比较两组患者的治疗效果,观察两组患者的生活质量,对比两组患者的不良反应.结果 实施利培酮治疗患者的治疗效率(84.09%)比实施利培酮联合阿立哌唑治疗患者的治疗效率(93.18%)低.实施利培酮治疗患者的社会关系、心理功能、生理功能、认知功能、角色功能等生活质量评分低于实施利培酮联合阿立哌唑治疗的患者.实施利培酮联合阿立哌唑治疗患者的头痛、失眠、震颤等不良反应情况比实施利培酮治疗的患者轻.结论 利培酮联合阿立哌唑治疗精神分裂症患者效果良好,可改善患者的生活质量,降低患者不良反应的发生率,治疗安全系数较高,对患者后续治疗及康复有着重要意义,建议在临床推广应用.
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