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研究人类的乳腺癌肿瘤疾病需要建立能够模拟乳腺癌的肿瘤动物模型,理想的人类乳腺癌动物模型的建立是研究乳腺癌生长和转移生物学以及寻求抗癌新药和治疗新方法的重要工具。乳腺癌细胞种植在裸鼠体内的解剖部位对乳腺癌细胞的生物学行为有着重要影响,并且乳腺癌细胞的生长需要同源组织间质的支持。所以为了更好地模拟人类的乳腺癌,建立MX-1人乳腺癌细胞原位裸鼠肿瘤模型,即将MX-1人乳腺癌细胞直接接种到裸鼠乳房。
The study of human breast cancer tumor needs to establish a tumor animal model that can simulate breast cancer. The establishment of an ideal animal model of human breast cancer is an important tool for studying the growth and metastasis of breast cancer, finding new anticancer drugs and treating new methods. The implantation of breast cancer cells in the anatomical site of nude mice has an important effect on the biological behavior of breast cancer cells, and the growth of breast cancer cells requires the support of interstitial tissue of the same tissue. Therefore, in order to better simulate human breast cancer, MX-1 human breast cancer cells in situ nude mice model established, about MX-1 human breast cancer cells directly into nude mice breast.