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目的 探讨广州市职业健康监护评价结果与死亡的相关性。方法 利用 1989～ 1992年广州市实施职业健康监护 (OHS)系统中建立的 399家工厂中≥ 35岁的 78785名职工的个体健康档案为基础资料 ,按前瞻性队列研究方法 ,随访至 1998年 12月 31日 ,了解队列中职工的生存状态和死亡情况 ,并进行 χ2 检验和Cox模型分析。结果 (1)队列中 78785名职工随访 8年 ,共 6 2 76 35人年(男性 3892 40人年 ) ,总死亡人数为 15 2 5人 ,总死亡率为 2 43.0 / 10万人年 (男 330 .4/ 10万人年、女10 0 .3/ 10万人年 )。 (2 )队列中男女职工有职业接触史者分别为 46 .1%和 34.4% ,建档时有吸烟史男女职工分别占 70 .3%和 1.5 %。 (3)无论男性或女性 ,总死亡率与OHS评价结果均有明显相关 ,调整年龄、文化程度、吸烟与职业接触等因素后 ,评价为追踪观察或异常者与评价为健康或大致健康者比较 ,其相对危险度 (RR)分别为男 :1.85 (95 %CI为 1.5 8～ 2 .18)和 2 .71(95 %CI为 2 .39～ 3.0 8) ,女 :1.80 (95 %CI为 1.2 2～ 2 .6 4)和 2 .89(95 %CI为 2 .17～ 3.86 ) ;进一步分析肿瘤、心脑血管疾病等主要死因死亡率与OHS评价结果间的相关性 ,结果与上述相似。 (4 )男性中年组 (35～ 49岁 )OHS评价为追踪观察或异常者 ,心脑血管疾病?
Objective To investigate the correlation between occupational health monitoring evaluation and death in Guangzhou. Methods Based on the individual health records of 78,785 workers aged 35 or above from 399 factories established in the Occupational Health Monitoring (OHS) system in Guangzhou from 1989 to 1992, according to a prospective cohort study, follow-up was conducted until December 1998 On the 31st of the month, understand the survival status and death of workers in the cohort and conduct χ2 test and Cox model analysis. Results (1) 78,785 employees in the cohort were followed up for 8 years for a total of 6,276,350 person years (3892 40 person-years for men), with a total death toll of 15,251 and a total fatality rate of 243,000 / 100,000 person-years 330. 4/10 million person-years, and 10 0/3/100 thousand person-years). (2) There were 46.1% and 34.4% of male and female workers in the cohort who had a history of occupational exposure, respectively, with a smoking history of 70.3% and 1.5% respectively. (3) There was a significant correlation between the total mortality rate and the OHS evaluation results in both males and females. After adjusting for age, education level, smoking and occupational exposure, the evaluation of follow-up observation or abnormality was compared with that of the evaluation of healthy or general health , Relative risk (RR) were 1.85 (95% CI 1.58 ~ 2.18) and 2.71 (95% CI 2.39 ~ 3.08), respectively, and 1.80 (95% CI 95% 1.2 2 ~ 2.64) and 2.89 (95% CI 2.17 ~ 3.86); further analysis of tumor, cardiovascular and other major causes of mortality and OHS evaluation of the correlation between the results and the results similar to the above . (4) Male middle-aged group (35-49 years old) OHS evaluation for follow-up observation or abnormal, cardiovascular and cerebrovascular diseases?