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运用双抗体夹心法检测了33例结核性脑膜炎(结脑)和30例非结脑病人的脑脊液(CSF)中的可溶性白细胞介素-2受体(SIL-2R)。分析了急性期、亚急性期、恢复期结脑CSF中SIL-2R水平。结果显示:结脑患者CSF中SIL-2R水平与对照组相比有极显著性差异(P<0.001)。急性期、亚急性期结脑患者CSF中的SIL-2R水平与恢复期比较有显著差异(P<0.05),结果提示了CSFSIL-2R可作为结脑诊断、病情监测及预后的评估指标之一
The soluble interleukin-2 receptor (SIL-2R) in cerebrospinal fluid (CSF) from 33 cases of tuberculous meningitis (tuberculous meningitis) and 30 cases of non-tuberculous meningitis was detected by double antibody sandwich method. The levels of SIL-2R in CSF of acute, subacute and convalescent nodules were analyzed. The results showed that the level of SIL-2R in CSF of tuberculosis patients was significantly different from that of the control group (P <0.001). CSF levels of SIL-2R in patients with subacute nocturnal encephalopathy were significantly different from those in recovery phase (P <0.05), suggesting that CSFSIL-2R could be used as a diagnostic index in tuberculosis diagnosis, disease surveillance and prognosis one