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1976年Chou首先在一慢性多发性肌炎病人的肌肉标本中发现Myxovirus样的构造,Yunis与Samaha在1971年首先以包涵体肌炎(inclusion body myositis)来称呼此一肌肉病变,包涵体肌炎在临床表现如一慢性多发性肌炎,而病理变化上的特色为冷冻的肌肉标本切片以H＆E染色,可发现有镶边的空泡状结构,内含嗜硷性颗粒而电子显微镜下,可在细胞质或细胞核内发现丝状之包涵体。包涵体肌炎一般认为是偶发性的疾病,而病理上与远端肌病变(distal myopathy)和眼因肌失养性病变(Oculopharyngeal muscular dystrophy)相关。
In 1976 Chou first found a Myxovirus-like construct in a muscle specimen of a patient with chronic polymyositis. Yunis and Samaha first referred to this muscle lesion, inclusion body myositis, in 1971 as inclusion body myositis In clinical manifestations such as a chronic polymyositis, and pathological changes characterized by frozen muscle specimens sectioned with H & E staining, can be found with a striped vacuolar structure, containing alkyne-based particles and electron microscopy, available at Filamentous inclusions are found in the cytoplasm or nucleus. Inclusion body myositis is generally considered a sporadic disease and is pathologically related to distal myopathy and Oculopharyngeal muscular dystrophy.