血管中血液产生的剪切力和血液流动类型调节血管的许多自稳过程,如血管的重塑、心脏发育和动脉粥样硬化的形成。动脉粥样硬化损伤在血管的高层流剪切流区不易发生,在低剪切力或受干扰区如血管分支处则易发生。排列于血管中的内皮细胞可感知血管壁所受的不同机械压力。近期的研 Shear forces and blood flow patterns generated by the blood in the blood vessel regulate many of the self-stabilizing processes of the blood vessel, such as vascular remodeling, cardiac development and atherosclerosis formation. Atherosclerotic lesions in the blood flow in the high shear flow area is not easy to occur, in low shear or disturbed area such as the vascular branch is prone. Endothelial cells arranged in blood vessels can sense different mechanical stresses on the vessel wall. Recent research