人类和实验动物中存在心脏功能和铁代谢的性别相关差异。男性患者和雄性动物模型更易患心肌病和心力衰竭。然而,在铁超负荷性心肌病中是否存在类似差异并不清楚。方法和结果:雄性和雌性野生型小鼠和铁调素调节蛋白(hemojuvelin)缺陷小鼠分别注 There are gender-related differences in cardiac function and iron metabolism in humans and laboratory animals. Male patients and male animal models are more susceptible to cardiomyopathy and heart failure. However, it is unclear whether similar differences exist in iron overload cardiomyopathy. Methods and Results: Male and female wild-type mice and hemojuvelin-deficient mice were injected