手足口病是由多种肠道病毒引起的常见传染病,人是肠道病毒的唯一宿主,对CoxA16及EV71型肠道病毒普遍易感〔1〕。一般患者症状轻微,以发热和手、足、口腔等部位的皮疹、疱疹为主要特征。大多数手足口病患儿预后良好,属于自限性疾病。但少数患儿可并发脑膜炎、脑炎、肺出血、肺水肿、呼吸循环衰竭等严重并发症,可致不同程度的后遗症,甚至死亡,严重威胁小儿身体健康〔2〕。该中心是湖北地区手足 Hand, foot and mouth disease is caused by a variety of enterovirus common infectious disease, human is the only host of enterovirus, CoxA16 and EV71 type enterovirus generally susceptible 〔1〕. The general symptoms of patients with mild fever and hand, foot, mouth and other parts of the rash, herpes as the main feature. Most children with hand, foot and mouth disease prognosis is good, are self-limiting disease. However, a small number of children may be complicated by meningitis, encephalitis, pulmonary hemorrhage, pulmonary edema, respiratory failure and other serious complications, can cause varying degrees of sequelae, and even death, a serious threat to children’s health (2). The center is hand and foot in Hubei Province