口腔颌面部的组织器官在发育、形成和正常生理过程中 ,不仅存在着细胞的增殖、分化 ,而且伴随着细胞凋亡(ａｐｏｐｔｏｓｉｓ)。同时细胞凋亡也是畸形、肿瘤、自身免疫性疾病、病毒、细菌感染等口腔疾病的重要发病机制[1,2 ] 。目前细胞凋亡与口腔疾病的关系正日益受到关注 ,运 Oral and maxillofacial tissues and organs in the development, formation and normal physiological processes, not only the existence of cell proliferation, differentiation, and accompanied by apoptosis (apoptosis). At the same time apoptosis is also an important pathogenesis of deformities, tumors, autoimmune diseases, viruses, bacterial infections and other oral diseases [1,2]. At present, the relationship between apoptosis and oral diseases is receiving increasing attention