神经纤维瘤病常侵犯皮肤、神经系统、肌肉、骨骼及眼部。症状在出生或童年表现出来,但青春期、妊娠期或更年期症状变得更为明显。最近遇见一个连续两代五人发病的家族,其中子代四人中二人有眼部症 Neurofibromatosis often invades the skin, nervous system, muscles, bones, and eyes. Symptoms manifest themselves at birth or childhood, but the symptoms of puberty, gestational or menopause become more pronounced. Recently I met a family of five people who had two consecutive episodes. Two of the offspring had eye problems.