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本研究应用免疫学检测方法，对胃癌患者围手术期血清ＩＬ－２及ｓＩＬ－２Ｒ水平进行了动态观察。结果表明：１．胃癌患者术前免疫功能是低下的；２．去瘤后经过创伤应激反应期的免疫抑制状态后，免疫功能显著改善；３．创伤应激反应的免疫抑制期时间比较短（一般在７２ｈ以内）；４．术后近、远期动态监测ＩＬ－２和ｓＩＬ－２Ｒ水平可以判断手术的彻底性，并对判断有无复发有重要临床意义；５．术后给予具有免疫调节作用的细胞因子治疗是非常必要的。同时推测：胃癌易患人群的ＩＬ－２水平可能低于正常人，这对胃癌普查具有重要意义
In this study, immunological assays were used to observe the serum levels of IL-2 and sIL-2R in patients with gastric cancer during the perioperative period. The results show that: 1. The preoperative immune function of gastric cancer patients is low; After the tumor had undergone the immunosuppressive state of the traumatic stress reaction period, the immune function improved significantly; 3. The period of immunosuppression of traumatic stress response is relatively short (usually within 72h); 4. The dynamic monitoring of IL-2 and sIL-2R levels in the near and far after operation can determine the thoroughness of the operation and have important clinical significance in judging whether or not there is recurrence.5. It is necessary to administer cytokine therapy with immunomodulatory effect after surgery. At the same time, it is speculated that the level of IL-2 in gastric cancer susceptible population may be lower than normal, which is of great significance for the general survey of gastric cancer.