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一例草绿色链球菌所致的亚急性细菌性心内膜炎患者对β-内酰胺抗生素治疗无效,尽管该菌对此药明显敏感。在这种病例中,抗生素的杀菌浓度(最小杀菌浓度MBC)与抑菌浓度(最小抑菌浓度MIC)之间的比率是10或大于10(试管内草绿色链球菌对药物敏感度的试验数值)。但由这种链球菌造成的治疗问题至今尚未提出。作者报告2例病例(另1例确诊为与第1例相同的耐药菌株感染)。病例报告:
An example of subacute bacterial endocarditis caused by Streptococcus viridans is ineffective in the treatment of β-lactam antibiotics, although the bacteria are clearly sensitive to this medicine. In this case, the ratio between the bactericidal concentration of the antibiotic (minimum bactericidal concentration MBC) and the bacteriostatic concentration (minimum inhibitory concentration MIC) is 10 or greater (in vitro test values for susceptibility of S. oleifera to drugs ). However, the treatment problems caused by this Streptococcus have not been proposed so far. The authors reported two cases (the other one confirmed the same as the first case of the same drug-resistant strains of infection). Case Reports: