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目的探讨术后内置125Ⅰ球囊内照射治疗脑胶质瘤的临床效果。方法自2003年4月-2003年10月,采用125Ⅰ充填球囊内照射方法治疗脑胶质瘤患者4例。近距离放射治疗剂量为60-80Gy,持续照射5-8d。结果随访一年1例死亡,生存3例,3例患者卡氏评分均较治疗前有明显提高。随诊期内未出现严重并发症。结论125Ⅰ充填球囊内照射治疗脑胶质瘤方法简便,可提高患者的生存质量和延长患者的生存时间,不会导致严重并发症,是治疗胶质瘤的一种有效的方法。
Objective To investigate the clinical effect of intracranial 125 Ⅰ balloon irradiation in the treatment of glioma. Methods From April 2003 to October 2003, 4 patients with glioma were treated with 125 I balloon-infusing method. Brachytherapy dose of 60-80Gy, continuous exposure 5-8d. Results One year follow-up died and survived in 3 cases. The Karnofsky scores of 3 patients were significantly higher than those before treatment. No serious complications occurred during the follow-up period. Conclusion 125I balloon-filled intracavity irradiation treatment of glioma is simple, can improve the quality of life of patients and prolong the survival time of patients without causing serious complications, is an effective method for the treatment of gliomas.