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交界性卵巢肿瘤(BOT)又称为低度潜在恶性肿瘤,在组织学上界于良性及恶性之间,无肿瘤细胞间质浸润,但有恶性细胞的特点。1973年,WHO将卵巢交界性肿瘤列入卵巢肿瘤的分类,成为一种独立的病理类型,且仅限于上皮性肿瘤。现将其发病因素总结如下。1 生殖因素1.1 妊娠次数 妊娠对卵巢交界性肿瘤的发生具有保护作用,且随生育次数的增多,其保护作用增加。Harlow和Riman报道,生育≥3次者与未生育妇女比较,发生卵巢交界性肿瘤的危险性可减少60％左右。1.2 首次生育年龄Parazzini等的研究资料表明,初次生育
Borderline ovarian tumors (BOT), also known as low-grade potential malignant tumors, are histologically characterized by benign and malignant tumors without interstitial infiltration of tumor cells but with malignant characteristics. In 1973, WHO classified ovarian borderline tumors as a classification of ovarian tumors, becoming an independent pathological type and limited to epithelial tumors. The incidence of factors are summarized below. 1 Reproductive factors 1.1 The number of pregnancies Pregnancy has a protective effect on the occurrence of borderline ovarian tumors, and with the increase of the number of births, its protective effect increases. Harlow and Riman have reported that the risk of borderline ovarian tumors can be reduced by about 60% when compared with those without childbirth for ≥3 times. 1.2 The first birth age Parazzini other research data show that the first childbearing