胃癌是最常见的恶性肿瘤之一,在分子生物学及遗传学研究中发现胃癌的发生与端粒酶激活、基因不稳定性、癌基因激活和抑癌基因失活等多种因素和多基因损伤有关,其中抑癌基因的失活在胃癌发生发展中更常见、更重要。Runx3是新发现的在迄今为止约10余种和胃癌相关的基因中与胃癌关 Gastric cancer is one of the most common malignant tumors. In the study of molecular biology and genetics, gastric cancer was found to be associated with multiple factors such as telomerase activation, gene instability, oncogene activation and inactivation of tumor suppressor genes, Injury, in which tumor suppressor gene inactivation in the development of gastric cancer is more common, more important. Runx3 is a newly discovered gene that has been linked to gastric cancer in about 10 genes related to gastric cancer so far