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迄今,又有两组研究单位报道了与作者相同的发现,即急性淋巴细胞白血病(AL-L)患者中存在的t(1;19)易位.有趣的是,三组描述的这类易位,其断裂点仅有微小的区别.Williams等明确断裂点为t(1;19)(q23;p13.3),Carroll等报道的是t(1;19)(q23;q13),而作者发现的是t(1;19)(q21;q13).很明显,这些断裂点的差异甚微,每例均为相同的易位.但作者与Carroll等难于准确分析19号染色体的长臂或短臂,因
To date, two groups of researchers have reported the same findings as the authors, namely t(1;19) translocations in patients with acute lymphoblastic leukemia (AL-L). Interestingly, the three groups described this type of The fracture point has only a slight difference. Williams et al. defined the fracture point as t(1;19)(q23;p13.3), and Carroll et al. reported t(1;19)(q23;q13). It was found that t(1;19)(q21;q13). It is obvious that these breakpoints have little difference, and each case is the same translocation. However, it is difficult for the author and Carroll to accurately analyze the long arm of chromosome 19 or Short arm due to