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近年来,不少报告提示自律神经活动可能与冠状动脉痉挛性心绞痛有密切关系。作者对冠状动脉痉挛性心绞痛患者的日内心绞痛发作前后自律神经活动的变化和做为副交感神经活动指标的心电图R—R间期变化系数(CV)的测定意义进行了探讨。这次探讨用CV做为交感神经活动的指标。CV不受心得安(10mg静注)的影响,同硫酸阿托品(0.5mg/kg静注)后,CV从6.5±0.6%下降到1.0±0.2%。用去甲肾上腺素使血压升高时,CV明显增加,在其增加前用阿托品处理可使之明显消失,而CV与心率
In recent years, many reports suggest that autonomic nervous activity may be closely related to coronary artery spasm angina. The authors investigated the changes of autonomic nervous activity before and after intraday angina pectoris in patients with coronary artery spastic angina and the significance of determining the inter-R-R interval coefficient of variation (CV) as an index of parasympathetic nerve activity. This discussion uses CV as an indicator of sympathetic activity. CV was not affected by propranolol (10 mg iv), CV decreased from 6.5 ± 0.6% to 1.0 ± 0.2% after atropine sulfate (0.5 mg / kg iv). With norepinephrine to raise blood pressure, CV increased significantly before the increase with atropine treatment can make it significantly disappear, and CV and heart rate