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前列腺特异抗原（ＰＳＡ）是目前最佳的前列腺癌肿瘤标志物。我们对２５４例包括前列腺素、非前列腺癌和部分正常人血清ＰＳＡ值进行了分析、以４ｎｇ／ｍｌ为正常参考值，其相应的灵敏度、特异度、阳性预测值、阴性预测值分别为８２．２％、８２．８％、５７．５％、９４．３％。ＰＳＡ还可为是否行前列腺穿刺活检提供依据。当ＰＳＡ≤４ｎｇ／ｍｌ时，患者可暂无须行穿刺活检，仅有５．７％的风险。而当ＰＳＡ＞１０ｎｇ／ｍｌ时，应即行穿刺，其中将有７１．７％的病例为前列腺癌患者。如ＰＳＡ在４～１０ｎｇ／ｍｌ之间，可结合直肠指检或其他检查决定是否行穿刺活检。
Prostate-specific antigen (PSA) is currently the best prostate cancer tumor marker. We analyzed the serum PSA values of 254 patients including prostaglandin, non-prostate cancer and some normal people. The sensitivity, specificity, positive predictive value and negative predictive value of the serum PSA of 4ng / ml were 82% and 82%, respectively. 2%, 82.8%, 57.5%, 94.3%. PSA can also provide a basis for whether prostate biopsy is performed or not. When PSA ≤ 4ng / ml, the patient can temporarily without biopsy, only 5.7% of the risk. When PSA> 10ng / ml, puncture should be performed immediately, of which 71.7% of patients will be prostate cancer patients. Such as PSA between 4 ~ 10ng / ml, can be combined with digital rectal examination or other examination to determine whether the line biopsy.