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目的探讨口服孟鲁司特联合复方异丙托溴铵雾化吸入在毛细支气管炎中的治疗作用。方法对160例患儿随机分成三组,(Ⅰ)口服孟鲁司特加压缩雾化吸入复方异丙托溴铵,(Ⅱ)复方异丙托溴铵压缩雾化吸入,(Ⅲ)对照组,三组均给予抗病毒、止咳化痰、支持疗法等综合治疗,给药5～7d。结果Ⅰ组患儿病程、临床症状缓解明显优于Ⅱ、Ⅲ组(P<0.01),差异有统计学意义。结论口服孟鲁司特联合复方异丙托溴铵在毛细支气管炎治疗中效果明显,值得临床推广应用。
Objective To investigate the therapeutic effect of oral montelukast combined with ipratropium bromide inhalation in bronchiolitis. Methods 160 children were randomly divided into three groups: (Ⅰ) oral montelukast plus inhalation of compound ipratropium bromide; (Ⅱ) compound ipratropium bromide inhalation; (Ⅲ) control group , Three groups were given antiviral, cough and phlegm, supportive therapy and other comprehensive treatment, administration 5 ~ 7d. Results The course of disease and clinical symptoms in group Ⅰ were significantly better than those in groups Ⅱ and Ⅲ (P <0.01). The difference was statistically significant. Conclusion oral montelukast combined with ipratropium bromide in the treatment of bronchiolitis effect is obvious, it is worthy of clinical application.