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作者选择病程1月以上的脑梗塞患者10例(男4例,女6例,平均年龄71.2岁)。首先静脉注射锝~(99m)-6-甲丙二肟(~(99m)Tc-HMPAO),(3.7～7.4)×10~8Bq或10～20mci(1Ci=3.7×10~(10)Bq),10min后服用Ibudilast(脑循环改善药)20mg,4h后进行第1次SPECT;再立即静脉注射~(99m)Tc-HMPAO(7.4～14.8)×10~8Bq或20～40mci,进行第2次SPECT。将第2次SPECT与第1次相比,用视觉判定CT低密度区域周边部位放射能变化来评价缺血部位脑血流,有改善者为阳性,没有改善者为阴性,介于两者之间为临界。结果:阳性5例,阴性3例,临界2例。
The authors chose 10 patients with cerebral infarction over 1 month (4 males and 6 females, mean age 71.2 years). (99m) Tc-HMPAO, 3.7 ~ 7.4 × 10 ~ 8Bq or 10 ~ 20mci (1Ci = 3.7 × 10 ~ 10 Bq) , 10 mg of Ibudilast (brain circulation improvement drug) 20 mg was given for 4 hours, and then the first SPECT was performed 4 hours later, and then 99m Tc-HMPAO (7.4-14.8) × 10 -8 Bq or 20-40 μm was intravenously injected SPECT. The second SPECT compared with the first, the visual determination of low-density CT area around the radioactive changes to assess the ischemic site of cerebral blood flow, there are positive for improvement, no improvement was negative, ranging between the two Between the critical. Results: Positive in 5 cases, negative in 3 cases, critical in 2 cases.