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目的 探讨芦荟及其复方制剂对小鼠抗疲劳能力的影响。方法 昆明种雄性小白鼠96只,随机分成游泳和缺氧实验各3组,每组10只;记忆实验3组,每组12只。实验Ⅰ组、实验Ⅱ组分别以鲜芦荟汁和复方芦荟液灌胃,对照组以等量的生理盐水灌胃。28d后,测定其持续游泳时间、低压舱耐缺氧时间以及用避暗箱法测定其改善记忆能力的效果。结果 服用芦荟及其复方制剂后的小鼠游泳时间明显延长,与对照组比较差异有显著性意义(P<0.05)。复方芦荟组记忆障碍叫显改善(P<0.05),耐缺氧时问有延长的趋势。结论 芦荟对小鼠有抗疲劳作用。
Objective To investigate the effect of aloe vera and its compound preparations on the anti-fatigue ability of mice. Methods Ninety-six Kunming male mice were randomly divided into 3 groups of swimming and hypoxia experiments, 10 in each group, and 3 groups of memory experiments, 12 in each group. The experimental group I and experimental group II were given intragastric administration of fresh aloe vera juice and compound aloe vera respectively. The control group was given intragastric administration with equal amount of normal saline. After 28 days, the duration of swimming, the time of hypoxia tolerance in hypobaric chambers, and the effect of improving the memory ability were measured by the dark box method. Results After taking aloe vera and its compound preparation, swimming time of mice was significantly prolonged, and there was significant difference compared with the control group (P<0.05). The memory impairment in the compound aloe group was significantly improved (P<0.05), and there was a prolonged tendency to hypoxia. Conclusion Aloe vera has anti-fatigue effects on mice.