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目的:了解干部与农民血小板(PLT)减少的分布、PLT与生化参数的相关性,指导重点人群防治。方法:海拔2 800m地区体检干部与农民12 010人,其中干部3 731人农民8 379人,年龄分段以间隔10岁分组。采用贝克曼/库尔特diff2全自动血细胞分析仪检测PLT,血小板减少定义为<100.00×109/L。结果:血小板减少总检出率(%):9.95;血小板减少率(%)分布特点:农民群体高于干部群体(10.74%vs8.20%,P<0.001)、男性群体高于女性群体(11.63%vs8.42%,P<0.001),且随生理年龄段的增长呈梯度性升高分布趋势。PLT与生化参数Hb、TBIL、ALT有关联性。结论:农民、男性、增龄等是PLT减少重点高危群体,高原人PLT的习服是血液系统及机体整体习服密切关联的一部分。
OBJECTIVE: To understand the distribution of platelet (PLT) reduction in cadres and peasants, the correlation between PLT and biochemical parameters, and to guide the prevention and treatment of key population. Methods: There were 12 010 medical cadres and peasants in 2 800 m above sea level, including 3 371 peasants, including 8 379 cadres, separated by 10-year intervals. PLB was detected using a Beckman / Coulter diff2 automatic hematology analyzer and thrombocytopenia was defined as <100.00 × 109 / L. Results: The total detection rate of thrombocytopenia (%) was 9.95. The distribution of thrombocytopenia (%) was higher in peasant group than in female group (10.74% vs8.20%, P <0.001), male group was higher than female group % vs8.42%, P <0.001), and with the growth of the physiological age gradient gradient distribution trend. PLT and biochemical parameters Hb, TBIL, ALT associated. CONCLUSIONS: Farmers, men, and aging are the key PLT-reducing high-risk groups. PLT acci- dents in the plateau are closely related to the blood system and the overall body suit.