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目的评价药物治疗大龄弱视的疗效。方法对确诊为弱视(9～16岁)的门诊患者100例,随机分5组:用药组(A组、B组、C组、D组)和对照组。每组20例。用药组给予息宁控释片口服、胞二磷胆碱肌注。服药前后作视功能检查、随机点立体视检测、视觉电生理(P-VEP)检查并作对照,随防期6月～3年。结果各药物治疗组平均总有效率80%,平均立体视功能改善70%,治疗后,视觉电生理(P-VEP)P100潜时缩短,P100波幅上升。结论息宁控释片和胞二磷胆碱对大龄弱视患者有效,可提高大龄弱视患者的视功能、改善立体视。
Objective To evaluate the efficacy of drug treatment of elderly amblyopia. Methods One hundred outpatients diagnosed as amblyopia (9-16 years old) were randomly divided into 5 groups: treatment group (A group, B group, C group, D group) and control group. 20 cases in each group. The drug group was given oral control tablets, citicoline intramuscular injection. Before and after taking medication as visual function test, random point stereopsis test, visual electrophysiology (P-VEP) examination and control, with the anti-6 months to 3 years. Results The average total effective rate was 80% and the average stereopsis function was improved by 70% in each drug treatment group. After treatment, P100 latency of visual electrophysiology (P-VEP) shortened and the amplitude of P100 increased. Conclusion Xining tablet and citicoline are effective for the elderly patients with amblyopia, can improve the visual function of elderly patients with amblyopia, improve stereopsis.