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本实验用岩参和攀枝花复合剂,观察对亚硝胺诱发小鼠前胃癌变的抑制和治疗作用。实验表明,当开始喂亚硝胺时就施以岩参和攀枝花复合用药(亚岩攀Ⅰ组)。在第5个月药物无明显抑制作用;在第7个月,对Ⅲ级早期癌和Ⅵ级浸润癌均有非常显著的抑制作用,但对广泛浸润癌的抑制作用不明显。在喂亚硝胺3个月后再给动物岩参和攀枝花复合用药(亚岩攀Ⅱ组),在第7个月,仅对Ⅲ级早期癌有显著疗效,而对浸润癌以后各级癌变不见疗效。如将亚岩攀Ⅰ组和Ⅱ组进行对比,早期癌和浸润癌在亚岩攀Ⅰ组中的发生率均低于Ⅱ组,统计学处理分别为显著及非常显著差异。这说明亚岩攀Ⅰ组用药的方式,对肿瘤发生的抑制作用大而且明显。
In this experiment, the inhibitory and therapeutic effects of nitrosamine-induced mouse precancerous lesions were observed using the compound of Panax ginseng and Panzhihua. Experiments showed that when the nitrosamines were started to be fed, the combined use of rock ginseng and Panzhihua was applied (Yanyan Pan I group). In the 5th month, there was no significant inhibition of the drug; in the 7th month, there was a very significant inhibitory effect on grade III early cancer and grade VI invasive carcinoma, but the inhibitory effect on extensive invasive carcinoma was not obvious. After 3 months of feeding nitrosamines, animals were given combined administration of Radix Ginseng and Panzhihua (Yamayan II group). In the 7th month, only the early stage III cancer had a significant effect, and after invasive cancer, all levels of cancer were changed. No effect. If the sub-rock climbing group I and group II were compared, the incidence of early cancer and invasive cancer in the sub-rock climbing I group was lower than the II group, statistical treatment was significant and very significant difference. This shows that the sub-rock climbing group I medication, the inhibition of tumorigenic and significant.