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本文选用体重2．5kg以上，育龄健康雄兔及3只雄免与之交配。随机分成交配前用药、交配后用药、交配前后均用药及对照四大组，每大组再分数小组以观察免交配前后不同时间使用壬苯醇醚（由淀粉、甘油、壬未醇醚药膜、蒸馏水混匀加热成青，药物含量25mg／ml），02％新法尔灭水溶液，0．02％醋酸洗必泰水溶液，壬苯醇醚药膜（50mg／张）等外用避孕剂的避孕效果。交配前用药即交配前将膏剂2ml或药膜一张子交配前10min送入阴道深处；交配后用药即交配后2min内将药物送入阴道深处或立即用水溶液5ml冲洗阴道，结果见表。李免交配前后不同时间使用几种避孕刘避孕控系观往由表中结果提示：①交配前后同时用药组避孕效果最好，避孕率达IO0％。②交配后用药比交配前用药避孕效果好，这可能是兔生殖生理机理机制与人类的差异所致。其中尤以王苯醇醚药膜组效果为佳，这可能是由于其药膜较易被阴道分泌液稀释、溶解，在阴道内滞留时间较长，作用持久有关。③交配后即时药物水溶液冲洗阴道与温开水冲洗阴道避孕效果相同（57％，P＞0．05），说明温开水冲洗避孕是避孕失败和无防备时性交后最易选择的简便、快捷、安全、有效的补救避孕方法。
This article selects the body weight of 2.5kg or more, healthy male rabbits and three male mating with it. Randomly divided into pre-mating medication, post-mating medication, medication before and after mating and control four major groups, each large group re-divided into groups to observe the different time before and after non-mating with nonoxynol (starch, glycerin, , Distilled water mixed into warm blue, drug content 25mg / ml), 02% nephelium aqueous solution, 0.02% chlorhexidine acetate solution, nonoxynol ether film (50mg / Zhang) and other topical contraceptive contraceptive effect . Before mating, the drug is applied before mating 2ml or a piece of film before mating 10 minutes into the vagina deep vaginal delivery; that is, within 2min after mating the drug into the vagina or within 5min immediately wash the vagina with water solution, the results shown in Table . Li different time before and after mating with the use of several contraception Liu contraceptive control system to the results from the table suggest: ① the same time before and after mating contraceptive effect of the best, contraceptive rate of IO0%. (2) The effect of contraception after mating was better than that before contracting, which may be caused by the difference of reproductive physiology mechanism between rabbits and human beings. Which Wangwang alcohol ether membrane group effect is better, which may be due to its more susceptible to vaginal fluid membrane dilution, dissolution, retention in the vagina longer, the role of long-lasting. ③ post-mating instant solution of aqueous solution of vaginal and warm water washing vaginal contraception with the same effect (57%, P> 0.05), indicating that warm water washing contraception is a contraceptive failure and non-prepared when the most easy to choose after intercourse easy, fast and safe Effective remedial contraceptive methods.