谷胱甘肽转移酶(Glutathione transfe—rase,简称GTase)是催化谷胱甘肽的亲核硫原子和另一个底物的亲电子基团反应的酶。这类酶广泛存在于生物界内,一般认为在细胞内对诱变剂、突变剂,和其它生理毒性化学物质起到解毒作用。谷胱甘肽(Glut—athione简称GSH)主要存在于需氧生物中,它是一种结构为γ—谷氨酰—半胱氨酰—甘氨酸的三肽,为某些酶的辅酶,其功能是保护酶和其它蛋白质巯基的一种抗氧化剂。 Glutathione transferase (GTase) is an enzyme that catalyzes the reaction of a nucleophilic sulfur atom of glutathione with an electrophilic group of another substrate. Such enzymes are widely present in the biological world, generally believed that detoxification agents, mutants, and other physiologically toxic chemicals play a detoxification effect in the cell. Glutathione (Glut-athione referred to as GSH) is mainly present in aerobic organisms, it is a structure of γ-glutamyl-cysteinyl-glycine tripeptide, for some enzyme coenzyme, its function Is an antioxidant that protects enzymes and other protein sulfhydryl groups.