结节性硬化症是由单一常染色体显性遗传引起的复合性发育不良。本病特征为皮损、智力迟钝及癫病。我们见到一例患者合并多系统损害，现报告如下。1临床资料患者，女，45岁。9岁以来面部鼻两侧出现淡棕色皮损，躯干部逐渐出现给节样皮损，呈正常皮色，无自觉症状，皮损逐渐增大 Tuberous sclerosis is a composite dysplasia caused by a single autosomal dominant inheritance. The disease is characterized by skin lesions, mental retardation and epilepsy. We see one patient with multiple system damage, the report is as follows. 1 clinical data, female, 45 years old. 9 years old since the nose appeared on both sides of the light brown skin lesions, trunk gradually appear to section-like lesions, showed normal skin color, no symptoms, skin lesions gradually increased