论文部分内容阅读
青海高海拔地区１４８例患儿尿素酶试验中，幽门螺杆菌（Ｈｅｌｉｃｏｂａｃｔｅｒ ｐｙｌｏｒｉ，ＨＰ）感染阳性检出率为４９．６％，明显高于沿海的浙江地区（Ｐ＜０．０１）。而在本地区，小儿在不同性别，城乡居住以及与成人相比较，ＨＰ检出阳性率无明显差异（Ｐ＞０．０５），胃粘膜微小结节样隆起中，ＨＰ检出阳性率明显增高（Ｐ＜０．０１）。ＨＰ感染在胃体、胃窦部、十二指肠球部的分布是不均匀的，以胃窦部为最高（Ｐ＜０．０１）。由于ＨＰ感染的直接毒性作用和免疫损伤等、可使浅表性胃炎发生并向萎缩性胃炎进展，积极消除ＨＰ感染，可能对预防癌前病变及肿瘤的发生有一定价值，这对于胃癌调整死亡率居全国之首位的青海地区有重要意义。
Helicobacter pylori (HP) infection was detected in 148 cases of urease test in Qinghai at a high altitude of 49.6%, which was significantly higher than that in Zhejiang (P <0.01). In the region, there was no significant difference in the positive rate of HP detected in children living in different genders, urban and rural areas and adults compared with adults (P> 0.05). The positive rate of HP in gastric mucosal nodules was significantly higher (P <0.01). HP infection in the gastric body, gastric antrum, duodenal bulb distribution is uneven, with the highest part of the antrum (P <0.01). Due to the direct toxicity of HP infection and immune damage, etc., can make the occurrence of superficial gastritis and progression to atrophic gastritis, and actively eliminate HP infection may prevent the occurrence of precancerous lesions and tumors of some value, which adjusted for the death of gastric cancer Qinghai area, which ranks first in the country, is of great significance.