论文部分内容阅读
目的探讨比较连续性肾脏替代疗法与自动腹膜透析治疗重症急性肾衰竭患者的临床效果。方法选取2012年7月至2016年2月营口市中心医院诊治的重症急性肾衰竭患者82例为研究对象,按随机抽签法分为观察组和对照组,每组41例。观察组患者采用连续性肾脏替代疗法,对照组患者采用自动腹膜透析治疗,比较两组患者治疗前后肾功能指标变化及并发症发生情况。结果 1治疗前,观察组和对照组患者的血肌酐、尿素氮和C反应蛋白水平比较,差异均无统计学意义(均P>0.05);治疗后,观察组患者的血肌酐、尿素氮水平及C反应蛋白水平均明显低于对照组,差异均有统计学意义(均P<0.01);2观察组患者的并发症发生率为4.9%,低于对照组的26.8%,差异有统计学意义(P<0.01);3观察组患者治疗后血流动力学指标优于对照组,差异有统计学意义(P<0.05)。结论相对于自动腹膜透析疗法,连续性肾脏替代疗法对重症急性肾衰竭的治疗效果更佳,可以显著改善患者的肾功能,维持血流动力学平稳,并发症较少,安全性较高。
Objective To investigate the clinical effects of continuous renal replacement therapy and automatic peritoneal dialysis in patients with severe acute renal failure. Methods From July 2012 to February 2016, 82 patients with severe acute renal failure diagnosed and treated in Yingkou Central Hospital were enrolled and divided into observation group and control group according to random sampling method, with 41 cases in each group. Patients in the observation group were treated with continuous renal replacement therapy. Patients in the control group were treated with automatic peritoneal dialysis. Changes in renal function and complications were compared between the two groups before and after treatment. Results 1 Before treatment, the levels of serum creatinine, urea nitrogen and C-reactive protein in the observation group and the control group were not significantly different (all P> 0.05); after treatment, the serum creatinine, blood urea nitrogen And C-reactive protein levels were significantly lower than the control group, the differences were statistically significant (all P <0.01); 2 observation group patients complication rate was 4.9%, lower than the control group, 26.8%, the difference was statistically significant (P <0.01) .3 The hemodynamic indexes of the observation group were better than those of the control group after treatment, the difference was statistically significant (P <0.05). CONCLUSIONS: Compared with automatic peritoneal dialysis, continuous renal replacement therapy is more effective in treating severe acute renal failure, which can significantly improve renal function, maintain stable hemodynamics, fewer complications and higher safety.